Is Guelph worth visiting?

Yes, it has great parks and historic architecture.

How long is the drive?

It takes about 5 hours and 30 minutes.

No, there are no tolls on this route.

Yes, you can take a train from Cornwall to Guelph via VIA Rail and GO Transit.

What is the best time to visit?

Spring and autumn are the best times.

Guelph

Driving

St Andrews West to Guelph

Updated: 28 May 2026

The journey from St Andrews West to Guelph covers approximately 500 kilometers along the Highway 401 West corridor. Driving takes about 5.5 hours, depending on traffic in the Greater Toronto Area. Guelph is a major city in the Waterloo Region, known for its historic architecture and the University of Guelph. This route is a standard path for those traveling to the western side of the GTA. Expect heavy traffic as you approach the Guelph area.

Total Distance: 500 km driving distance, 470 km straight-line air distance.

Fastest Way

Driving via the 401 is the fastest route, taking 5.5 hours.

Cheapest Way

Driving is the only practical way to reach Guelph from St Andrews West.

Compare St Andrews West to Guelph Routes

Driving

Direct

Duration

5 hours 30 mins

Avg Price

85-95 CAD in fuel

Operator

Personal Vehicle

Route

Highway 401 West.

The 401 is the most direct route; watch for heavy traffic near the GTA.

Travel Tips

Navigation
Use the 401 exit for Highway 6 to reach downtown Guelph.
Dining
Check out the local restaurants in the downtown area.
Weather
Guelph can be humid in the summer; plan for indoor activities if needed.
Parking
There are several municipal parking lots in downtown Guelph.
Timing
Avoid rush hour traffic on the 401 when entering the GTA.

Safety Tips

Highway Safety
The 401 is a busy highway; stay alert and maintain a safe distance.
Emergency
Keep a roadside emergency kit in your car.
Visibility
Use your headlights during the day to increase visibility.
Pedestrian Safety
Use crosswalks in the busy downtown area.