The drive from Saint John to Sherbrooke is approximately 750 kilometers. You will travel west on the Trans-Canada Highway (Route 2) through New Brunswick, cross into Quebec, and take Highway 20 and Highway 55 to reach the Eastern Townships. The drive takes about 8 hours. This route is a scenic journey through the Appalachian region.
Total Distance: 750 km driving distance; 550 km straight-line air distance.
The drive is long; plan for a stop in Rivière-du-Loup.
Autumn for the spectacular fall colors in the Eastern Townships.