Mississauga
Mississauga
Guelph
Guelph
Train Driving

Mississauga to Guelph

Updated: 29 May 2026

Guelph is located west of Mississauga in Wellington County. The distance is approximately 60 kilometers. Driving via Highway 401 is the most direct route. The GO Train Kitchener line also serves the city, providing a direct connection to Union Station. It is a historic city with a beautiful downtown.

Total Distance: Driving distance is 60 km; straight-line air distance is 50 km.
Fastest Way
Driving is the fastest method outside of peak hours.
Cheapest Way
GO Transit is the most affordable way to travel.
Compare Mississauga to Guelph Routes
Train
Direct
Driving
Direct
Duration 1 hour 10 minutes 50 minutes
Avg Price $12-$18 $12-$18 in fuel
Operator GO Transit Personal Vehicle
Route GO Train Kitchener Line Highway 401 West
Tip Check the schedule for weekend service. Highway 401 can be very busy.
Travel Tips
  • Traffic
    Avoid the 401 during peak hours.
  • Parking
    Parking is available in downtown Guelph.
  • Weather
    Check for winter road conditions.
  • Comfort
    Bring comfortable walking shoes.
  • Planning
    Check local event schedules.
Safety Tips
  • Road Safety
    Be careful on the busy 401 highway.
  • Personal Security
    Keep your belongings secure.
  • Night Safety
    Be cautious when driving at night.
  • Emergency
    Keep an emergency kit in your car.
People Also Ask
  • Is Guelph far?
    It is about 60 km from Mississauga.
  • Can I take the train?
    Yes, the GO Train serves Guelph.
  • Is it a nice city?
    Yes, it is known for its historic charm.
  • Are there hotels?
    There are many hotels and motels.
  • Is it part of the GTA?
    It is often considered part of the Greater Toronto Area.
Quick Info
  • From Mississauga, Ontario, Canada
  • To Guelph, Ontario, Canada
  • Modes
Best Time to Travel

Autumn is beautiful for the fall colors.

Things to Do in Guelph
1
Riverside Park
A beautiful park with a lake and gardens. It is great for a relaxing walk.
2
Guelph Civic Museum
Features a collection of local history.
3
Basilica of Our Lady Immaculate
A stunning historic church.
4
University of Guelph
A world-renowned university with a beautiful campus.
Tags
Mississauga to Guelph GO Train Guelph Highway 401 Guelph travel Wellington County commute from Mississauga Ontario travel Guelph attractions